PNPLA3 and TLL-1 Polymorphisms as Potential Predictors of Disease Severity in Patients With COVID-19
Cell and Developmental Biology
[키워드] 95% CI
absence
ACE2
Admission
Affect
angiotensin-converting enzyme 2
binding
characterized
cleavage site
Clinical course
Comorbidity
consecutive patient
contribute
Course
COVID-19
death
determinant
disease course
early phase
Genetic polymorphism
Genetic variant
Genotype
higher risk
host cell
host gene
host receptor
host’s cells
IFNL3
immune stimulation
in silico
increased risk
infect
Infection
Inflammation
Intensive
involved
MERTK
Mild
nasopharyngeal swabs
NLRP3 inflammasome
nucleic acid
older patient
outcome
pandemic
Pathogenesis
pathogenesis of COVID-19
pathway
Patient
PNPLA3
PNPLA3 I148M
polymorphism
Potential
predicted
Predictive
Prognosis
protease
Protease activity
Protein
protein cleavage
re-infect
Reinfection
risk
SARS-CoV-2
SARS-COV-2 infection
Severity of disease
Sex
significantly
Specific
spike
subject
subsequent
Support
the SARS-CoV-2
the Spike
therapeutic approaches
therapy
tissue damage
TLL-1
upregulation
variant
were assessed
younger patient
[DOI] 10.3389/fcell.2021.627914 PMC 바로가기 [Article Type] Cell and Developmental Biology
[DOI] 10.3389/fcell.2021.627914 PMC 바로가기 [Article Type] Cell and Developmental Biology